A joint NO-Age and NADIS Meeting
Date: 26 March 2026
Time: 13:00 – 17:30 (CET)
Format: In-Person
Cost: Free Registration
Location & Address
Domus Medica, Auditorium L-200 Sognsvannsveien 9, 0372 Oslo, Norway
Welcome Message
Nicotinamide adenine dinucleotide (NAD⁺) is a central redox cofactor and the limiting substrate of key metabolic enzymes that include the sirtuin family of protein deacylases, the poly(ADP-ribose) polymerases (PARPs), and the cyclic ADP-ribose (cADPr) synthases.
The constellation of cellular functions in which these enzymes are involved makes NAD⁺ availability critical for cell survival, and its depletion is a leading factor in a number of human diseases. Primary deficiencies of NAD⁺ homeostasis are the result of impaired biosynthesis, while secondary deficiencies can arise due to other factors, such as increased NAD⁺ consumption or a dietary deficiency of its vitamin B3 precursors.
NAD⁺ depletion can manifest in a wide variety of pathological phenotypes, ranging from rare inherited defects to more common multifactorial, often age-related, diseases. In fact, the exhaustion of intracellular NAD⁺ levels is currently considered a major contributor to aging and has been associated with the onset of age-related complications such as dementia, cancer, obesity, and reproductive aging. In contrast, NAD⁺ repletion strategies—such as the administration of NAD⁺ precursors—show great promise in preventing or ameliorating the outcomes of these complications.
Meeting Scope & Featured Speakers
Hosted in Norway, this joint meeting brings together national and international leaders in the field to explore the latest breakthroughs in NAD⁺ biology. Leading European experts from the NADIS network will present their cutting-edge data across multiple disciplines, including:
- Aging & Longevity: Molecular mechanisms of systemic aging and NAD⁺ decline.
- Metabolism & Adipose Tissue: The role of NAD⁺ and related enzymes in thermogenic adaptations, brown adipose tissue activation, and white fat “browning.”
- Neuroscience: Neurodegeneration and cognitive preservation.
By facilitating interdisciplinary discussions and collaborations, we aim to drive innovation toward a future of healthy aging and improved treatments for age-related diseases.
➔ Following the scientific symposium, there will be a public forum (“Stay Young – How we keep our energy when we get older”) to disseminate these findings, and everyone interested is warmly invited to join us from 19:00 to 20:30 at Domus Bibliotheca.
Program
13:00 – 17:30 | NADIS Symposium: “NAD⁺ Horizons: Charting the Next Wave of Research”
Session I — PI Presentations & Keynote
- 13:00 – 13:20 — Carles Cantó Alvarez
- 13:20 – 13:40 — Riekelt Houtkooper
- 13:40 – 14:00 — Santina Bruzzone
- 14:00 – 14:20 — Morten Scheibye-Knudsen
- 14:20 – 15:00 — Mathias Ziegler (Keynote Speaker)
15:00 – 15:20 | Coffee Break
Session II — PI Presentations & Keynote
- 15:20 – 15:40 — Michela Deleidi
- 15:40 – 16:00 — George Janssens
- 16:00 – 16:20 — Ruben Zapata Perez
- 16:20 – 16:40 — Evandro Fei Fang
- 16:40 – 17:20 — Hilde Loge Nilsen (Keynote Speaker)
17:20 – 17:30 | General Discussion & Closing Remarks
Organizers
- Evandro Fei Fang-Stavem
- Johannes Frank
- The NADIS Consortium
Download this afternoon programme (11 March 2026 version) (here)
Flyer for this afternoon programme + an evening programme of the same day (11 March 2026 version)(here)
